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Patient
Education
SKIN
& BLOOD
Allergy Testing
SET/RAST/MRT |
Understanding “Allergies” What we call
“allergic reactions” are actually a hypersensitivity to substances
known as allergens, which normally do not cause a reaction. According to
one source, roughly 20% of the U.S. population has at least one form of
this disorder of the immune system. Some of the more common allergic conditions
or associated symptoms include: eczema, allergic rhinitis, bronchial asthma,
hives, and food allergies. Allergens may enter the body through a variety
of routes, including skin contact (jewelry, cosmetics, etc.), ingestion
(food products), inhalation (pollen, molds, etc.) and injection (drugs).
Hypersensitivities range from minor skin rashes to potentially lethal anaphylactic
shock, and therefore may be merely inconvenient, or dangerous. Understanding,
isolating and treating them is our concern at Alabama ENT.
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Making Sense of
Allergy Testing…
In order to get a complete picture of a patient’s allergy profile,
results from traditional Skin or S.E.T. (serial endpoint
titration) testing, RAST (RadioAllergoSorbent
Test), and the MRT blood test (Mediator Release
Test) will provide all the “pieces of the puzzle.” Both
the RAST and MRT can be performed from
a single blood draw done with a very small needle for your comfort.
Also, the Two-Week Food Diary that you were given will
also be very helpful in identifying food intolerances or allergies, since
only a limited number of foods can be tested for in any single allergy
panel. Also, since the foods you consume most frequently are the most
likely candidates for triggering your symptoms, the evaluation of your
food diary will help us identify foods which need to be added to the standard
food panel
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S.E.T. Testing…
S.E.T. skin testing involves injecting a tiny amount of a suspected allergen
under the skin in weaker to stronger concentrations, then waiting 15 minutes
and measuring the skin response to determine if an allergy exists. The
needles used for this testing are extremely small and only produce mild
discomfor
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RAST Testing…
RAST allergy testing can be used to determine IgE reactions
to foods and items that are airborne called “inhalants,” such
as dust mites, pollen, animal dander and molds. IgE reactions are the
quickest to take effect (usually between minutes and three hours) after
eating, inhaling or contacting a particular allergen. When allergic reactions
become life threatening, as in situations when the throat closes and the
patient cannot breathe, an IgE reaction is the culprit. Occasionally a
negative RAST test will occur while the patient contineus to have allergy
symptoms. A limited skin testing battery (S.E.T. test) may then be done
to rule out allergies in this case. Please be
aware that most insurance companies cover a large portion of RAST testing
or skin (S.E.T.) testing. However, before having your blood drawn, you
must meet with our Insurance Specialist to determine your particular insurance
benefits regarding the testing recommended by our doctors.
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MRT Testing…
Another type of reaction, IgG reactions, generally
occur more slowly and their symptoms may not be as apparent. However, they
can also wreak havoc on the body. IgG reactions can cause congestions, eczema,
and the other types of reactions commonly seen, but they can also be responsible
for for stomach and intestinal discomfort, headaches, itching and other
skin reactions, mood swings, fluid retention, even hyperactivity and attention
deficit in children and adults. Many people have reactions to foods that
are detrimental to their health, yet they do not involve the immune system.
Therefore they are not true allergies, but rather food intolerances. The
MRT identifies IgG allergies as well as food intolerances. This test exposes
whole blood (not just serum, the clear part) to the test items and measures
the change in the shape of the blood cells. It provides important information
about how a food affects the body. This information has enabled us to help
many of our patients who suffer from headaches, nasal congestion or coughing,
eczema, ADD/ADHD, or even multiple sclerosis improve dramatically. Although
the MRT is used extensively in Europe, U.S. insurance companies do not generally
pay for this test. Therefore, we offer it to our patients at our cost of
$385.00, since most patients must pay for it themselves.
(This test regularly costs over $600 when
billed by outside labs.)
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Preparing
For Allergy Testing…
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Discontinue antihistamines prior to testing.
Before blood is drawn for your allergy tests, you should have discontinued
use of any over-the-counter antihistamines (E.g. Benadryl, Chlortrimeton,
Claritin, etc.) for 48 hours. Prescription antihistamines such as
Allegra, Clarinex, Zyrtec and Astelin nasal spray should be discontinued
5 days prior to having blood drawn.
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Wait 3 weeks after last dose of steroids.
This precaution includes steroid injections (Decadron, Depomedrol)
and oral steroids (Prednisone). Steroid nasal sprays (Nasonex,
Rhinocort, Nasacort, Nasarel, Flonase) should be discontinued
5 days before testing.
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Allow 2 weeks after last dose of steroids before drawing
blood for MRT.
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Children should be well-hydrated before MRT and RAST
testing. Children should be given frequent liquids
for the entire morning and lunch hour prior to their testing. Failure
to do so may complicate the blood draw, resulting in unnecessary
stress on the child. It is sometimes necessary to draw blood from
more than one site to obtain adequate volume for the testing.
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The MRT must be drawn after 12:00 noon.
The samples must be sent by Airborne Express to the testing facility
within a few hours of being drawn in order to insure accurate results.
If you need to see the doctor on the same day that you plan to have
your MRT drawn, you will need to make your appointment after lunch;
from 1:00 PM to 3:00 PM. This will allow your blood to be prepared
for shipping before Airborne picks up specimens from our office.
If you are returning to the office only to have your blood drawn,
for the RAST or MRT, you will not need an appointment. Simply come-in
between 1-3PM and let the receptionist know that you are here for
a blood draw.
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Test Results…
When we receive the results of your allergy tests, our
allergy nurse will contact you regarding inhalants (airborne allergies).
Skin test results will be obvious the day of testing, and explained at
that time. We will also contact you about any sensitivity to foods, dyes
or additives. You will be invited to make an appointment with your doctor
to discuss these results and for possible follow-up referral to a qualified
dietician, if food allergy or intolerance is detected, to help you investigate
possible dietary changes. If for some reason you are not contacted
within two weeks of your RAST/MRT blood draw, please contact our office.
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Copyright 2005 Alabama ENT Associates
- Last Revised: 05/02/05 |